VIMM Newsletters
Jan 2024 New approach to pancreatic cancer treatment, shows promise for increased survival and expands therapeutic grid
Oct 2023 Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis
Sept 2023 Establishment of Humanized Mouse Models to Study Drug Function
Aug 2023 The crosstalking immune cells network creates a collective function beyond the function of each cellular constituent during the progression of hepatocellular carcinoma
July 2023 Scavenger Receptor A Is a Major Homeostatic Regulator that Restrains Drug-Induced Liver Injury
June 2023 Pancreatic Cancer: Basic Mechanisms and Therapies
April 2023 Epigenetic Regulation of Cancer in Response to Chemotherapy
Jan 2023 Innovative approach to study contact-specific gene regulation during embryogenesis
Dec 2022 Cell Competition in Carcinogenesis.
Sept 2022 Melanoma Differentiation Associated Gene-9/Syndecan Binding Protein/Syntenin-1 Promotes Hepatocellular Carcinoma.
Aug 2022 Chk1 Inhibition Potently Inhibits Phosphorylation and Activation of the STAT3 Transcription Factor in Human Multiple Myeloma Cells.
May 2022 Enhanced cancer therapy using a next generation engineered designer cytokine as a monotherapy and in combination with an immune checkpoint inhibitor.
Mar 2022 Breast cancer dormancy and immunotherapy
Sept 2021 Pharmacological Inhibition of the Nucleosome Remodeling Factor (NURF) with Bromodomain Inhibitors Controls TNBC Cancer Growth.
Jun 2021 Pharmacological Inhibition of MDA-9/Syntenin Blocks Breast Cancer Metastasis Through Suppression of IL-1β.
May 2021 Engineering T Cells to Express Tumoricidal MDA-7/IL-24 Enhances Cancer Immunotherapy
Mar 2021 EGFR-YTHDF2-cholesterol Axis Promotes Invasive Growth of Glioblastoma
Feb 2021 Highlights on recent research from Drs. Eva Lancaster and Timothy York
Jan 2021 PLK1 induces chromosomal instability and overrides cell cycle checkpoints to drive tumorigenesis
Nov 2020 Scavenger receptor-A is a biomarker and effector of Rheumatoid Arthritis: A large-scale multicenter study
Oct 2020 Genetic and Epigenetic Changes in YTHDF3 Promote Multiple Steps of Breast Cancer Brain Metastasis
Sept 2020 Hypoxia Helps Cancer Cheat in Cell Competition
Aug 2020 Breast cancer dormancy and immunotherapy
July 2020 Lumefantrine: an anti-malarial drug shows promise for glioblastoma treatment
June 2020 New Review Article: COVID-19 as an acute inflammatory disease
Feb 2020 Paul B. Fisher, MPh, PhD, FNAI, the Founding Director of VIMM Receives Virginia Catalyst Grant
Nov 2019 VIMM scientist reports that the Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells In Vitro and In Vivo
Sept 2019 Dr. Swadesh K. Das elected as a NAI (National Academy of Inventors) senior member
June 2019 VIMM Member update
May 2019 VIMM Scientist Have Discovered a Novel Regulatory Mechanism Governing Mitotic Function of Polo-like Kinase 1 (PLK1)
Mar 2019 MDA-7/IL-24 Suppresses DICER
Dec 2018 VIMM Member Updates
Oct 2018 Astrocyte Elevated Gene-1 (AEG-1) Regulates Macrophage Activation in Hepatocellular Carcinogenesis
Sept 2018 Gr1-/low CD11b-/low MHCII+Myeloid Cells Boost T Cell Anti-Tumor Efficacy
Aug 2018 Recombinant MDA-7/IL-24 Suppresses Prostate Cancer Bone Metastasis Through Down Regulation of the Akt/Mcl-1 Pathway
Jul 2018 Co-Targeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells
May 2018 Research from VIMM Scientists Establish a Link Between MDA-9/Syntenin and Protective Autophagy in Anoikis-Resistance Identifying an Achilles' Heel of Glioblastoma Multiforme
Apr 2018 Research from VIMM Scientists Establishes the Importance of MDA-9/Syntenin/IGF 1R/STAT3 Axis in PC Progression
Mar 2018 The Challenge of Multiple Myeloma (MM) and Targeting Cell Death Pathways in MM
Feb 2018 VIMM Member Updates
Jan 2018 Tumor Dormancy: A Natural By-Product of Evolutionary Survival Mechanisms
Dec 2017 VIMM Member Updates
Nov 2017 miRNA and Cancer
Oct 2017 Regulation of MicroRNA by MDA-7/IL-24
Sept 2017 Dissecting Mechanisms that Regulate the Epithelial Barrier in Healthy Gut and During Musosal Inflammation
Aug 2017 Astrocyte Elevated Gene-1 (AEG-1) Regulates Nonalcoholic Steatohepatitis (NASH)
Jul 2017 Determing Cell Signaling Pathways Mediating the Cytotoxicity of Melanoma Differentiation Associated Gene-7/Interleukin-24 (MDA-7/IL-24) in Lung Cancer
May 2017 A New Look at the Roles of PLK1 in Prostate Cancer
Apr 2017 Targeting Epigenetic Complexes to Achieve a Novel Cancer Immunotherapy
Feb 2017 Promoting Protective Antitumor Immunity for Cancer Eradication
Jan 2017 Attacking Therapeutic Resistance in Aggressive Brain Tumors
Dec 2016 Molecular Targeted Immunotherapy for Eradication of Prostate Cancer
Nov 2016 A Potential Path to Enhanced Therapy of Pancreatic and Other Cancers